Ciclopirox 8% Solution – 6 g

APO Ciclopirox contains ciclopirox 8% w/w, a topical antifungal medication formulated as a nail lacquer for the treatment of onychomycosis, a fungal infection of the fingernails or toenails. It is manufactured by Apotex and is currently listed by Health Canada as a marketed prescription medication.

Ciclopirox has broad antifungal activity and works differently from azole and allylamine antifungal drugs. Its mechanism is believed to involve binding to polyvalent metal ions such as iron and aluminum, which interferes with metal dependent enzymes and other cellular processes required for fungal metabolism and survival.

When applied directly to the nail, ciclopirox penetrates the nail plate and surrounding keratinized tissue, allowing the active ingredient to reach fungal organisms located within the nail. This local delivery is designed to reduce fungal growth while limiting systemic exposure compared with oral antifungal therapy.

APO Ciclopirox is intended to be used as part of a broader nail treatment program that may include regular removal or trimming of loose and infected portions of the nail in addition to consistent topical treatment. The manufacturer’s patient information specifically emphasizes ongoing nail care as part of treatment.

This product provides:

• Active Ingredient: Ciclopirox
• Strength: 8% w/w
• Quantity: 6g
• Dosage Form: Topical Nail Lacquer / Solution
• Manufacturer: Apotex Inc.
• Primary Use: Fungal Nail Infections (Onychomycosis)
• Applicator: Brush applicator

Health Canada lists APO Ciclopirox as a prescription topical medication with DIN 02298953. The product is supplied as a clear, colorless to slightly yellow solution in a 6g glass bottle fitted with an applicator brush.

Because fungal nail infections grow out slowly with the nail, treatment can require consistent use over an extended period before a healthy nail fully replaces the affected area. Visible improvement may therefore occur gradually rather than immediately.

Potential local adverse effects can include redness, irritation, burning, itching, or changes around the treated nail and surrounding skin. Treatment should be discontinued and medical advice obtained if significant irritation or hypersensitivity develops.

APO Ciclopirox is for topical nail use only and should not be applied to the eyes, mouth, or other mucous membranes. Patients with conditions such as diabetes, peripheral neuropathy, or immunosuppression may require additional medical assessment before treatment.

APO Ciclopirox should be used according to the treatment plan provided by a qualified healthcare professional, including appropriate nail care and removal of infected nail material when recommended.